Nicole Blaquiere: search on Z-Library

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1

Monomeric targeted protein degraders

Hanan, Emily J., Liang, Jun, Wang, Xiaojing, Blake, Robert, Blaquiere, Nicole, Staben, Steven T

Journal:

Journal of Medicinal Chemistry

Year:

2020

File:

PDF, 1.48 MB

2020

2

ChemInform Abstract: Rapid Synthesis of 1,3,5-Substituted 1,2,4-Triazoles from Carboxylic Acids, Amidines, and Hydrazines.

Georgette M. Castanedo, Pamela S. Seng, Nicole Blaquiere, Sean Trapp, Steven T. Staben

Journal:

Year:

2011

File:

PDF, 85 KB

2011

3

A scaffold-hopping approach to discover potent, selective and efficacious inhibitors of NF-κB inducing kinase

Blaquiere, Nicole, Castanedo, Georgette, Burch, Jason, Berezhkovskiy, Leo, Brightbill, Hans, Brown, Suzanne, Chan, Connie, Chiang, Po-Chang, Crawford, James J., Dong, Teresa, Fan, Peter, Feng, Jianwen

Journal:

Journal of Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 1.50 MB

english, 2018

4

Development of a tripartite solvent blend for sustainable chromatography

Chardon, Florence M., Blaquiere, Nicole, Castanedo, Georgette M., Koenig, Stefan G.

Journal:

Green Chemistry

Year:

2014

Language:

english

File:

PDF, 798 KB

english, 2014

5

Decarboxylative Ketone Aldol Reactions: Development and Mechanistic Evaluation under Metal-Free Conditions

Blaquiere, Nicole, Shore, Daniel G., Rousseaux, Sophie, Fagnou, Keith

Journal:

Journal of Organic Chemistry

Year:

2009

Language:

english

File:

PDF, 2.99 MB

english, 2009

6

Aporphine Alkaloid Synthesis and Diversification via Direct Arylation

Marc Lafrance, Nicole Blaquiere, Keith Fagnou

Journal:

European Journal of Organic Chemistry

Year:

2007

Language:

english

File:

PDF, 320 KB

english, 2007

7

Discovery of thiazolobenzoxepin PI3-kinase inhibitors that spare the PI3-kinase β isoform

Staben, Steven T., Ndubaku, Chudi, Blaquiere, Nicole, Belvin, Marcia, Bull, Richard J., Dudley, Danette, Edgar, Kyle, Gray, Daniel, Heald, Robert, Heffron, Timothy P., Jones, Graham E., Jones, Mark, K

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2013

Language:

english

File:

PDF, 3.06 MB

english, 2013

8

Structure-Based Design of Tricyclic NF-κB Inducing Kinase (NIK) Inhibitors That Have High Selectivity over Phosphoinositide-3-kinase (PI3K)

Castanedo, Georgette M., Blaquiere, Nicole, Beresini, Maureen, Bravo, Brandon, Brightbill, Hans, Chen, Jacob, Cui, Hai-Feng, Eigenbrot, Charles, Everett, Christine, Feng, Jianwen, Godemann, Robert, Go

Journal:

Journal of Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 1.77 MB

english, 2017

9

Medicinal chemistry of inhibiting RING-type E3 ubiquitin ligases

Blaquiere, Nicole, Villemure, Elisia, Staben, Steven T

Journal:

Journal of Medicinal Chemistry

Year:

2020

File:

PDF, 2.78 MB

2020

10

Rapid Synthesis of 1,3,5-Substituted 1,2,4-Triazoles from Carboxylic Acids, Amidines, and Hydrazines

Castanedo, Georgette M., Seng, Pamela S., Blaquiere, Nicole, Trapp, Sean, Staben, Steven T.

Journal:

Journal of Organic Chemistry

Year:

2011

Language:

english

File:

PDF, 776 KB

english, 2011

11

ChemInform Abstract: Four-Component Synthesis of Fully Substituted 1,2,4-Triazoles.

Steven T. Staben, Nicole Blaquiere

Journal:

Year:

2010

Language:

english

File:

PDF, 71 KB

english, 2010

12

Four-Component Synthesis of Fully Substituted 1,2,4-Triazoles

Steven T. Staben, Nicole Blaquiere

Journal:

Angewandte Chemie International Edition

Year:

2010

Language:

english

File:

PDF, 306 KB

english, 2010

13

Discovery of 2-{3-[2-(1-Isopropyl-3-methyl-1 H -1,2–4-triazol-5-yl)-5,6-dihydrobenzo[f]imidazo[1,2- d ][1,4]oxazepin-9-yl]-1 H -pyrazol-1-yl}-2-methylpropanamide (GDC-0032): A β-Sparing Phosphoinositide 3-Kinase Inhibitor with High Unbound Exposure and Robust in Vivo Antitumor Activity

Ndubaku, Chudi O., Heffron, Timothy P., Staben, Steven T., Baumgardner, Matthew, Blaquiere, Nicole, Bradley, Erin, Bull, Richard, Do, Steven, Dotson, Jennafer, Dudley, Danette, Edgar, Kyle A., Friedma

Journal:

Journal of Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 1.28 MB

english, 2013

14

NF-κB inducing kinase is a therapeutic target for systemic lupus erythematosus

Brightbill, Hans D., Suto, Eric, Blaquiere, Nicole, Ramamoorthi, Nandhini, Sujatha-Bhaskar, Swathi, Gogol, Emily B., Castanedo, Georgette M., Jackson, Benjamin T., Kwon, Youngsu C., Haller, Susan, Les

Journal:

Nature Communications

Year:

2018

Language:

english

File:

PDF, 1.97 MB

english, 2018

15

Cis-Amide isosteric replacement in thienobenzoxepin inhibitors of PI3-kinase

Staben, Steven T., Blaquiere, Nicole, Tsui, Vickie, Kolesnikov, Aleksandr, Do, Steven, Bradley, Erin K., Dotson, Jenna, Goldsmith, Richard, Heffron, Timothy P., Lesnick, John, Lewis, Cristina, Murray,

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2013

Language:

english

File:

PDF, 1.21 MB

english, 2013

16

Antibody-Mediated Delivery of Chimeric Protein Degraders Which Target Estrogen Receptor Alpha (ERα)

Dragovich, Peter S., Adhikari, Pragya, Blake, Robert A., Blaquiere, Nicole, Chen, Jinhua, Cheng, Yun-Xing, den Besten, Willem, Han, Jinping, Hartman, Steven J., He, Jintang, He, Mingtao, Rei Ingalla,

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2019

File:

PDF, 610 KB

2019

17

Heteroarylation of Azine N-Oxides

Gosselin, Francis, Savage, Scott J., Blaquiere, Nicole, Staben, Steven T.

Journal:

Organic Letters

Year:

2012

Language:

english

File:

PDF, 789 KB

english, 2012

18

ChemInform Abstract: Heteroarylation of Azine N-Oxides.

Francis Gosselin, Scott J. Savage, Nicole Blaquiere, Steven T. Staben

Journal:

Year:

2012

File:

PDF, 49 KB

2012

19

Four-Component Synthesis of Fully Substituted 1,2,4-Triazoles

Steven T. Staben, Nicole Blaquiere

Journal:

Angewandte Chemie

Year:

2010

Language:

english

File:

PDF, 306 KB

english, 2010

20

Direct Intramolecular Arylation of Unactivated Arenes: Application to the Synthesis of Aporphine Alkaloids.

Marc Lafrance, Nicole Blaquiere, Keith Fagnou

Journal:

Year:

2005

File:

PDF, 16 KB

2005

21

Ruthenium-Catalyzed Dehydrogenation of Ammonia Boranes

Blaquiere, Nicole, Diallo-Garcia, Sarah, Gorelsky, Serge I., Black, Daniel A., Fagnou, Keith

Journal:

Journal of the American Chemical Society

Year:

2008

Language:

english

File:

PDF, 590 KB

english, 2008

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